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Here are the ratings for "My Favorite Mistake," straight from TVGuide.com:

Grey's (21.9 million) was down a half mil.

According to numerous rumors all over the web, the next episode - My Favorite Mistake - which was originally supposed to air on March 29, may actually air on March 22 - this upcoming Thursday! According to these reports, ABC wants to keep the Grey's lead-in on October Road, since it did MUCH better than Six Degrees when it premiered. However, nothing yet has been confirmed by ABC. Although the official website says it is airing on the 22nd, ABC Media Net is still reporting it's airdate as the 29th. Stay tuned for more updates on this!
(Also - My Favorite Mistake is not the spin-off episode as previously reported. That episode, which has yet to be titled, will be two hours long and is currently set to air on May 10th.)

UPDATE [6:54 PM]: A source on the ABC Message Boards e-mailed ABC to ask them, and here's the reply they got back -

The episode was originally scheduled to air March 29, but it should air on the 22nd now.

Best,
Amy Astley
ABC Media Relations

So, there you have it. My Favorite Mistake will be airing on March 22, 2007.

Not only did the title of Episode 319 get released (it's not confirmed yet, however), but there's also a spoiler about it too! My Favorite Mistake airs sometime in March. From HamAndEggs75 at the ABC Message Boards.

There only appears to be one patient, Cathy. There are also sides for her daughter, Nina. Cathy is sick, coughing, her CT showed that her coughing caused a hairline fracture in her rib and it close to puncturing her lung. She also mentions having cancer at another point in the sides so it could be lung cancer. Her daughter Nina is perfect, regrets taking her mom out to the mall during flu season and says they both knew better. Nina is uptight and bossy and worried the interns do not know what they are doing. Cathy should have surgery to fix her lungs but Nina is worried the risk is too high. There is a scene of Cathy yelling at Nina that "you can't be perfect, no one is perfect."